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Associations between respiratory diseases and lung cancer risk: a secondary analysis of the large-scale prospective UK biobank cohort - PubMed

4 hours ago
  • #Acute Infections
  • #Respiratory Diseases
  • #Lung Cancer Risk
  • Respiratory diseases are associated with increased lung cancer risk (HR 2.97).
  • Acute respiratory infections show strong associations with lung cancer incidence, especially viral pneumonia (HR 9.86).
  • Squamous cell carcinoma exhibits the highest risk elevation among subtypes (HR 3.65).
  • Neutrophil counts partially mediate the associations (up to 8% mediated).
  • Study uses UK Biobank cohort data with 2189 lung cancer cases over mean 10.44-year follow-up.