Cognitive Effects of Esketamine in Treatment-Resistant Depression: A Systematic Review - PubMed
3 hours ago
- #cognitive effects
- #treatment-resistant depression
- #esketamine
- Esketamine does not appear to cause cognitive deterioration in treatment-resistant depression.
- Improvements in attention and processing speed are the most consistent findings with esketamine use.
- Memory remains stable in short-term but may improve with extended follow-up.
- Executive functions show gains, especially in participants with baseline impairments and in long-term assessments.
- Esketamine may support functional recovery and complement its antidepressant effects.
- Further research is needed to better understand cognitive trajectories and personalize treatment strategies.