A closed tumor-immune-brain circuit in cancer cachexia - PubMed
4 days ago
- #tumor-immune-brain circuit
- #GDF15
- #cancer cachexia
- Cancer-associated cachexia is a metabolic syndrome causing weight loss and tissue wasting.
- Shi et al. discovered a GDF15-driven tumor-immune-brain circuit affecting metabolism and catabolism.
- The study highlights a novel crosstalk mechanism in cancer cachexia.