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Electroacupuncture Ameliorates Cyclophosphamide-Induced Ovarian Impairment in Rats With Diminished Ovarian Reserve and is Associated With Th17/Treg-Related Immune Modulation - PubMed

4 hours ago
  • #Diminished Ovarian Reserve
  • #Th17/Treg Immune Modulation
  • #Electroacupuncture
  • Electroacupuncture (EA) improves ovarian function in rats with diminished ovarian reserve (DOR) induced by cyclophosphamide.
  • EA treatment normalizes hormone levels, reduces granulosa cell apoptosis, and regulates the Bcl-2/Bax axis.
  • EA modulates the Th17/Treg immune balance by reducing pro-inflammatory cytokines and increasing regulatory factors.
  • Transcriptomic analysis shows EA enriches immune-related pathways, supporting its immunoregulatory role in DOR.