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Should We Do an Individual Management of Septic Shock in Neurocritically Ill Patients? A Proposal of a Conceptual Algorithm - PubMed

3 hours ago
  • #Neurocritical Care
  • #Septic Shock
  • #Hemodynamic Optimization
  • Septic shock (SS) is a severe condition with high mortality rates globally.
  • Neurocritically ill patients are particularly vulnerable to developing SS, partly due to invasive neuromonitoring devices like external ventricular drainage (EVD).
  • Early goal-directed therapy (EGDT) was initially recommended for SS management but is now debated due to high costs and patient heterogeneity.
  • An individualized approach is proposed for managing SS in neurocritically ill patients to improve outcomes.
  • A novel conceptual algorithm is suggested to optimize mean arterial pressure (MAP) and cerebral perfusion pressure (CPP) among other parameters.
  • The algorithm aims to enhance the DO2/VO2 ratio and neurological outcomes in these patients.