Exosomes in Skin Rejuvenation: Systematic Review of Anti-Aging Effects and Clinical Applications - PubMed

4 hours ago

Exosomes, as extracellular vesicles, enhance cell communication, transport bioactive substances, and influence immune responses, making them valuable in dermatology.
A systematic review of 21 articles found that exosome-based therapies improve skin elasticity, reduce wrinkle depth, enhance hydration, and modulate pigmentation.
Molecular evidence supports increased collagen and elastin synthesis, reduced oxidative stress, and suppression of matrix metalloproteinases from exosome treatments.
Therapies derived from sources like adipose stem cells, platelets, plants, and milk show favorable safety profiles with minimal adverse events and high patient satisfaction.
Exosome therapies represent a promising, minimally invasive approach for skin rejuvenation, but further standardized clinical trials are needed to confirm efficacy and long-term safety.

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