Indication of transfusion of blood components in paediatric and neonatal patients in India: Real-world multicentre data - PubMed
12 hours ago
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- #neonatal-transfusion
- #paediatric-transfusion
- High variability in paediatric transfusion practices globally, with most transfusions in low-income countries administered to children under 5 years.
- Study aimed to characterize epidemiology and indications for blood component transfusions among neonatal and paediatric patients in India.
- Prospective longitudinal multicentre study conducted over 6 months (April-September 2022) across 23 medical institutions.
- 52,658 (13.2%) of 396,092 total blood component requests were for paediatric patients, predominantly male (60.1%) and aged 5-12 years (26.4%).
- Red cell components most frequently requested (68%), followed by platelets (17.5%) and plasma (12.3%).
- Medical indications accounted for 67.6% of requests, with haematology (48%), oncology (17.1%), and infections (10.5%) being most common.
- Surgical indications accounted for 30.3%, with cardiac surgeries (44.2%) and gastrointestinal surgeries (30%) being most common.
- Haemoglobinopathies (21.4%) were the most common overall indication for transfusions.
- First large-scale epidemiological assessment of paediatric transfusion indications in India, providing foundational evidence for future research.