A perspective on the potential role of remote ischemic conditioning in post-stroke depression: Mechanisms and future directions - PubMed
a day ago
- #Post-stroke depression
- #Remote ischemic conditioning
- #Neuroprotection
- Post-stroke depression (PSD) is a common neuropsychiatric complication with a prevalence of 10-40%.
- Current treatments like SSRIs and SNRIs have limited efficacy and safety concerns.
- Remote ischemic conditioning (RIC) is a non-invasive intervention showing promise for PSD treatment.
- RIC activates protective pathways via neural, humoral, and immune mechanisms.
- Potential benefits of RIC include modulation of neuroinflammation, neuroplasticity, and cerebrovascular dysfunction.
- The article reviews shared mechanisms between PSD and classical depression and RIC's neuroprotective effects.
- Future research directions are outlined to optimize RIC for neuropsychiatric outcomes in stroke survivors.