Management Strategy for Anaphylaxis in a Patient With Suspected or Confirmed Mastocytosis: A Case Report - PubMed
4 hours ago
- #Mastocytosis
- #Emergency Medicine
- #Anaphylaxis
- Anaphylaxis is a severe, life-threatening systemic hypersensitivity reaction.
- Mastocytosis increases the risk of severe anaphylactic reactions.
- Case report: 31-year-old female with suspected mastocytosis experienced severe anaphylactic shock after an insect sting.
- Required mechanical ventilation and circulatory support due to cardio-respiratory failure.
- Insufficient response to intramuscular epinephrine necessitated continuous intravascular infusion.
- Treatment included intensive fluid therapy, antihistamines, glucocorticosteroids, and correction of acid-base disturbances.
- Patients with mastocytosis may require higher doses of adrenaline and continuous IV infusion for 1-2 days.
- Severe organ perfusion disturbances can lead to metabolic acidosis, requiring sodium bicarbonate infusion.
- Early admission to ICU is recommended for mastocytosis patients experiencing anaphylaxis.