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Comparative Efficacy and Safety of Treatments for Malignant Gastric Outlet Obstruction: A Systematic Review and Network Meta-analysis - PubMed

3 hours ago
  • #malignant GOO
  • #EUS-GJ
  • #network meta-analysis
  • The study compares treatments for malignant gastric outlet obstruction (GOO), including surgical gastrojejunostomy (GJ), stomach-partitioning GJ, endoscopic ultrasound-guided GJ (EUS-GJ), and enteral stent (ES).
  • EUS-GJ showed superior clinical success compared to other treatments (GJ, partitioning GJ, and ES).
  • ES was significantly inferior to EUS-GJ and surgical GJ in terms of reintervention rates.
  • No significant differences were observed in technical success and severe adverse events (SAEs) among treatments.
  • Surgical treatments (GJ and partitioning GJ) resulted in longer hospital stays compared to other methods.
  • EUS-GJ is concluded as the best treatment for malignant GOO, with ES being a less expensive but higher reintervention alternative.