Cohesin and its regulation promote monopolar kinetochore orientation at meiosis I in Arabidopsis - PubMed
5 hours ago
- #meiosis
- #kinetochore orientation
- #cohesin
- Cohesin subunits and regulation promote monopolar kinetochore orientation in Arabidopsis meiosis I.
- Mutants in cohesin-related components restore fertility in spo11 osd1 haploid plants, revealing key factors like REC8, SGO1/2, and SPF2.
- Monopolar orientation persists with crossovers despite sister kinetochore splitting and reduced cohesin levels at metaphase I.
- The study supports a conserved, cohesion-driven model for kinetochore orientation across eukaryotes.