Human herpesvirus evasion of humoral immunity and implications for vaccine development - PubMed
3 hours ago
- #herpesvirus
- #immune evasion
- #vaccine development
- Human herpesviruses have co-evolved with their hosts, developing specialized immune evasion strategies.
- These viruses establish lifelong infections and can cause severe diseases during immunosuppression, including graft rejection, cancer, and neurodegenerative diseases.
- Varicella zoster virus (VZV) is the only human herpesvirus with licensed vaccines available.
- The review discusses mechanisms of humoral immune evasion by herpesviruses and their implications for vaccine and treatment development.
- Developing strategies to prevent herpesvirus-associated diseases is a critical public health priority.