An obligatory role for AgRP neurons in maintaining body temperature during time-restricted feeding - PubMed
5 hours ago
- #AgRP neurons
- #time-restricted feeding
- #body temperature
- AgRP neurons are essential for maintaining body temperature during time-restricted feeding on low-calorie diets.
- Lesioning AgRP neurons leads to lethality due to hypothermia, not reduced food intake, during restricted feeding on chow but not on high-fat diets (HFD).
- AgRP neurons are crucial for adaptive feeding behaviors and motivational feeding on chow during time-restricted feeding.
- The study shows that AgRP neurons are activated during fasting in cold environments but not in warm ones.
- AgRP neurons are dispensable for body weight regulation when food is available ad libitum.