Defining Moderate Disease and Progression in Hidradenitis Suppurativa: An Expert Framework to Unlock the Window of Opportunity for Prompt Treatment - PubMed
2 days ago
- #Hidradenitis Suppurativa
- #Biologic Therapy
- #Disease Progression
- The concept of a therapeutic window of opportunity is crucial in treating hidradenitis suppurativa (HS), where early treatment can prevent irreversible skin damage.
- Moderate HS is defined by inadequate symptom control on conventional therapies, presence of one inflamed skin tunnel, or four or more inflammatory lesions across two or more areas.
- Disease progression in HS includes new or extended tunnels, persistent lesions in new areas, or an increase in lesion numbers in affected regions.
- Biologic therapies are currently approved only for moderate to severe HS, highlighting the need for clear definitions to guide treatment decisions.
- Expert frameworks aim to standardize definitions of moderate HS and progression to facilitate timely and effective treatment.