Charting the nerve-immune axis in endometriosis - PubMed
7 hours ago
- #Neuroimmune axis
- #Chronic pain
- #Endometriosis
- Endometriosis is a systemic disorder involving complex nerve-immune interactions, contributing to chronic pain and inflammation.
- Key events include abnormal sensory nerve growth and dysfunctional immune responses driving lesion development and pain.
- The neuroimmune interplay influences epithelial and stromal behavior, amplifies inflammation, and reinforces pain circuits.
- Targeting neuroimmune pathways presents new therapeutic opportunities to manage lesion progression and chronic pain in endometriosis.