Effects of continuous positive airway pressure therapy duration on patients with obstructive sleep apnoea and type 2 diabetes mellitus: a systematic review and meta-analysis - PubMed
3 hours ago
- #Type 2 Diabetes Mellitus
- #CPAP therapy
- #Obstructive Sleep Apnoea
- The study evaluates the effects of CPAP therapy duration on patients with OSA and T2DM.
- A systematic review and meta-analysis of 14 RCTs involving 1273 participants was conducted.
- CPAP therapy was categorized into short-term (<12 weeks), medium-term (12-<24 weeks), and long-term (≥24 weeks).
- Long-term CPAP intervention significantly reduced HOMA-IR levels (MD -1.67; 95% CI -2.57 to -0.77).
- Medium and long-term CPAP use increased BMI levels (MD 0.31 kg/m² and 0.74 kg/m², respectively).
- ESS scores significantly decreased with medium and long-term CPAP use (MD -1.45 and -1.79, respectively).
- No significant changes were observed in FBG, MBG, or HbA1c levels with CPAP duration.
- Longer CPAP use benefits insulin resistance and sleepiness but not glycaemic markers.