Diagnostic potential of total serum ghrelin in autoimmune gastritis: A systematic review and meta-analysis - PubMed
7 hours ago
- #Meta-analysis
- #Serum ghrelin
- #Autoimmune gastritis
- Autoimmune gastritis (AIG) is a chronic inflammatory condition affecting gastric parietal cells.
- The study conducted a systematic review and meta-analysis on the diagnostic potential of total serum ghrelin in AIG.
- Results showed no significant difference in total serum ghrelin levels between AIG patients and healthy controls overall.
- Subgroup analysis revealed significantly lower serum ghrelin levels in patients with moderate-to-severe gastric atrophy.
- Meta-regression identified BMI as a substantial contributor to heterogeneity among studies.
- The diagnostic utility of serum ghrelin in AIG requires further investigation due to high heterogeneity and study limitations.