Association Between Different Glucocorticoids and Mortality in ICU Patients With Sepsis-related Acute Respiratory Distress Syndrome: A Retrospective cohort study from MIMIC-IV Database - PubMed
4 hours ago
- #glucocorticoids
- #ARDS
- #mortality
- Methylprednisolone and dexamethasone were associated with lower 28-day mortality compared to hydrocortisone in ICU patients with sepsis-associated ARDS.
- High-dose glucocorticoid therapy (≥88 mg/day methylprednisolone equivalent) was linked to increased mortality versus low-dose therapy.
- The study was a retrospective cohort analysis of 896 patients from the MIMIC-IV database, with findings validated through subgroup analyses and propensity score matching.