Twenty-Year Follow-Up After Patent Foramen Ovale Closure in Patients With Paradoxical Embolism - PubMed
3 hours ago
- #long-term outcomes
- #PFO closure
- #paradoxical embolism
- Transcatheter closure of patent foramen ovale (PFO) is effective in preventing recurrent ischemic events in patients with PFO-associated embolism.
- The study followed 130 patients for 20 years after PFO closure, showing a low rate of recurrent stroke (0.04 per 100 patients per year) and transient ischemic attacks (0.25 per 100 patients per year).
- Recurrent ischemic events were more common in patients with thrombophilia (33% vs 4.8%).
- Bleeding events occurred in 13% of patients, with major bleeding in 6.9%, more frequently in women and those on long-term antithrombotic therapy.
- The study highlights the long-term safety and efficacy of PFO closure but suggests the need for personalized antithrombotic strategies to minimize bleeding risks.