MetALD at the crossroads of metabolic and alcohol-related liver disease - PubMed
3 hours ago
- #alcohol consumption
- #liver disease
- #MetALD
- MetALD is a new concept that categorizes individuals with metabolic dysfunction who consume alcohol beyond MASLD thresholds but below ALD criteria.
- MetALD is associated with increased mortality, severe liver outcomes like advanced fibrosis, cancer, and cardiovascular complications.
- Accurate diagnosis requires precise alcohol quantification; blood phosphatidylethanol is a key biomarker to address underreporting of alcohol intake.
- Integrated therapeutic approaches are needed to manage MetALD and improve patient outcomes, as discussed in this review.