SRPRB can regulate proliferation and migration in Triple-Negative breast cancer cells - PubMed
6 hours ago
- #SRPRB
- #triple-negative breast cancer
- #WNT signaling
- SRPRB is highly expressed in triple-negative breast cancer (TNBC) tissues and cell lines.
- High SRPRB expression correlates with poor overall survival and recurrence-free survival in TNBC patients.
- Knockdown of SRPRB inhibits TNBC cell proliferation, migration, and invasion while inducing apoptosis.
- SRPRB knockdown suppresses the WNT signaling pathway in TNBC cells.
- SRPRB serves as a prognostic biomarker and potential therapeutic target for TNBC.