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A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study - PubMed

7 hours ago
  • #stress
  • #anxiety
  • #ashwagandha
  • Study evaluates a proprietary ashwagandha root extract (APB) for stress and anxiety in healthy adults.
  • Randomized, double-blind, placebo-controlled trial with 141 participants aged 18-65.
  • Participants received 300 mg APB twice daily, ashwagandha root extract (ARE), or placebo for 8 weeks.
  • Primary endpoint: change in serum cortisol levels; secondary endpoints included stress and anxiety scales.
  • Significant reductions in cortisol, stress (PSS), anxiety (HAM-A), and mood improvements (POMS) observed.
  • APB showed superior efficacy compared to ARE and placebo in reducing stress and anxiety.
  • The proprietary ashwagandha extract is deemed safe and effective for stress and anxiety reduction.