Regulation of inflammatory gene transcription by ubiquitination and deubiquitination - PubMed
a day ago
- #inflammation
- #transcription
- #ubiquitination
- Transcriptional responses are triggered by pathogen recognition to combat inflammatory stimuli like infections.
- Inflammatory gene transcription must be tightly regulated to avoid harmful outcomes such as immunopathology.
- The ubiquitination-deubiquitination cycle plays a key role in controlling inflammatory gene transcription via NF-κB and interferon pathways.
- Understanding gene-specific mechanisms is crucial for regulating inflammatory gene transcription.