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The rate and predictors of recompensation in patients with decompensated cirrhosis due to metabolic dysfunction-associated liver disease (MASLD) - PubMed

a day ago
  • #cirrhosis
  • #recompensation
  • #MASLD
  • The study evaluates the rate and predictors of recompensation in patients with decompensated cirrhosis due to metabolic dysfunction-associated liver disease (MASLD).
  • Among 124 patients, the 2-year cumulative incidence of recompensation was 24%, with factors like MELD-Na score, albumin levels, ascites, and multiple decompensation events influencing outcomes.
  • Recompensation was frequently transient, and its survival benefit did not persist after adjusting for liver function and time-dependence.
  • The study highlights the importance of basal liver function in recompensation but notes that frequent further decompensation limits its prognostic impact on survival.
  • Key predictors included MELD-Na score (aSHR 0.891), albumin levels (aSHR 1.894), ascites (aSHR 0.475), and multiple decompensation events (aSHR 0.151).