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Biologically Younger Individuals, as Identified by MARK-AGE Biological Age Scores, Display a Distinct Favourable Blood Chemistry Profile Regardless of Age - PubMed

7 hours ago
  • #biomarkers
  • #ageing research
  • #biological age
  • The MARK-AGE Study identified biomarkers of ageing in a European population of 3,300 subjects aged 35-74.
  • A set of 10 biomarkers for females and 10 for males was used to calculate a 'bioage score' representing biological age.
  • Biologically younger individuals, as determined by the MARK-AGE score, showed favorable blood chemistry profiles, including higher HDL and Vitamin D levels.
  • Smoking females and individuals with Down Syndrome were found to be biologically older, while postmenopausal females on hormone replacement therapy were biologically younger.
  • Certain markers like glucose and HbA1c correlated with chronological age but not biological age difference, suggesting different roles in ageing processes.