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Neurophysiological Resting-State Markers of Catatonia in Schizophrenia and Mood Disorders - PubMed

4 hours ago
  • #catatonia
  • #EEG
  • #schizophrenia
  • Study identifies neurophysiological resting-state markers of catatonia in schizophrenia and mood disorders.
  • Patients with catatonia showed increased delta and gamma power, decreased alpha power, reduced peak alpha frequency (PAF), and longer mean duration of microstate C.
  • Findings suggest EEG could be used for diagnostic biomarker development, improving early detection and treatment of catatonia.
  • The study involved a case-control retrospective analysis of 102 patients with catatonia and 519 without, adjusting for age, sex, medication, and comorbid conditions.
  • Results indicate a probable neurodevelopmentally-related excitation/inhibition dysregulation underlying catatonia.