Rosemary Aqueous Extract as a Natural Alternative to Retinol for Skin Aging Intervention - PubMed

4 hours ago

Retinoids are the gold standard for topical anti-aging treatments but cause skin irritation, leading to demand for plant-based alternatives.
Rosemary aqueous extract (RE) regulates gene expression similarly to retinol and enhances collagen I synthesis.
RE protects against UVA-induced skin damage by preserving epidermal thickness and reducing inflammation.
RE demonstrates protective effects in an inflammaging model combining UVA irradiation and chronic cytokine stimulation.
RE downregulates TRPV1 expression in neuronal cells, suggesting potential to reduce skin itching sensation.
RE is positioned as a multifaceted anti-aging ingredient, suitable as a retinol alternative for sensitive skin.

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