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TDP-43 is coming to the cottage: A new tool to study neurodegenerative diseases - PubMed

3 hours ago
  • #TDP-43
  • #neurodegenerative diseases
  • #PLOS Biology
  • TDP-43 protein is lost from the nucleus and forms clumps in the cytoplasm in some neurodegenerative diseases.
  • A new study in PLOS Biology presents a system that models both TDP-43 pathologies.
  • The article is open access under the Creative Commons Attribution License.
  • The authors declare no competing interests.
  • The study references a cell-based reporter linking TDP-43 aggregation to dysfunction.