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Characterization of KLK5-high epithelial cells and their interactions with the tumor microenvironment in high-grade serous ovarian cancer - PubMed

4 hours ago
  • #Tumor Microenvironment
  • #HGSOC
  • #KLK5
  • Study focuses on KLK5-high epithelial cells in high-grade serous ovarian cancer (HGSOC).
  • Investigates interactions between KLK5-high cells and the tumor microenvironment (TME).
  • Utilizes single-cell and spatial transcriptomics for analysis.
  • Keywords include ECM remodeling and epithelial-stromal crosstalk.
  • Authors declare no competing interests.
  • References include studies on oncogenic proteins, tumor microenvironment, and ovarian cancer.
  • Funding sources include Shanghai Sailing Program and National Natural Science Foundation of China.