The Dual Role of Extracellular Vesicles in Aging and Age-Related Diseases: Pathophysiology and Therapeutic Potential - PubMed
12 hours ago
- #aging
- #therapeutic-potential
- #extracellular-vesicles
- Aging is a complex process leading to loss of physiological integrity and increased risk of chronic diseases.
- Extracellular vesicles (EVs) play a dual role in aging and age-related diseases, both contributing to pathology and offering therapeutic potential.
- EVs from senescent or diseased cells propagate inflammation, oxidative stress, and other harmful processes.
- EVs from stem cells or healthy tissues can restore balance, enhance function, and promote tissue repair.
- EVs hold promise as diagnostic biomarkers and treatments for aging-related conditions, despite challenges like rapid clearance.