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Pulsed field ablation for atrial fibrillation in patients with heart failure: insight from the ATHENA registrys - PubMed

7 hours ago
  • #pulsed field ablation
  • #atrial fibrillation
  • #heart failure
  • Study evaluated pulsed field ablation (PFA) outcomes in atrial fibrillation patients with heart failure (HF) using data from the ATHENA registry.
  • Patients were stratified into no HF, HF with preserved ejection fraction (HFpEF), and HF with mildly reduced or reduced EF (HFmrEF/rEF).
  • Primary endpoint was freedom from atrial arrhythmias >30 seconds after a 2-month blanking period.
  • Among 1,224 patients, 14.4% had HF; 1-year freedom from arrhythmias was higher in no-HF group (81.0%) versus HF group (73.3%).
  • In paroxysmal AF, no-HF patients had significantly higher arrhythmia-free rates (82.2%) than HF patients (68.6%); no significant difference in persistent AF patients.