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Pterostilbene inhibits ferritinophagy-mediated ferroptosis via the NRF2/NCOA4/FTH1 axis and alleviates intervertebral disc degeneration through nanoliposomal delivery - PubMed

4 hours ago
  • #Pterostilbene
  • #Ferroptosis
  • #Nanoliposome
  • Pterostilbene (PTE) inhibits ferritinophagy-mediated ferroptosis via the NRF2/NCOA4/FTH1 axis.
  • Nanoliposomal delivery enhances PTE's bioavailability and alleviates intervertebral disc degeneration in vivo.
  • PTE protects nucleus pulposus cells from oxidative stress and suppresses extracellular matrix degradation.