Chronic Kidney Disease Severity and Risk of Cognitive Impairment - PubMed
4 days ago
- #Medical Research
- #Cognitive Impairment
- #Chronic Kidney Disease
- Study investigates the association between chronic kidney disease (CKD) severity and cognitive impairment.
- 5607 participants from the Chronic Renal Insufficiency Cohort (CRIC) Study were analyzed.
- Key metrics: estimated glomerular filtration rate (eGFR) and urinary protein to creatinine ratio (UPCR).
- Cognitive functions assessed: global cognition, verbal memory, attention, processing speed, and executive function.
- Findings show higher UPCR and lower eGFR linked to increased risk of cognitive impairment.
- Patients with eGFR <60 mL/min/1.73 m² and UPCR ≥150 mg/g had a 38% higher risk of global cognition impairment.
- Study highlights CKD severity as a significant risk factor for cognitive decline.