Mitochondrial remodeling in skeletal muscle underlies exercise-induced reversal of age-associated functional decline in mice and humans - PubMed
3 hours ago
- #aging reversal
- #mitochondrial remodeling
- #exercise adaptation
- Exercise-induced improvements in functional capacity and reduced frailty in old mice depend on mitochondrial adaptations in skeletal muscle at structural, enzymatic, and functional levels.
- Mitochondrial dysfunction in skeletal muscle is linked to locomotor muscle function decline in the elderly, with exercise potentially mitigating this decline.
- Skeletal muscle mitochondria maintain plasticity during aging in both mice and humans, enabling improvements in muscle performance and functional capacity.