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Combined variations in sleep, physical activity, and nutrition and the risk of major adverse cardiovascular events - PubMed

4 hours ago
  • #preventive medicine
  • #cardiovascular health
  • #lifestyle behaviors
  • The study examines the combined effects of sleep, physical activity, and nutrition (SPAN) on major adverse cardiovascular events (MACE).
  • Optimal SPAN combination (8.0–9.4 h/day sleep, 42–104 min/day MVPA, DQS 32.5–50.0) reduces MACE risk by 57%.
  • A median SPAN score (52.8) is linked to a 41% lower MACE risk.
  • Minimum combined variation (+11 min sleep, +4.5 min MVPA, +3 DQS points) lowers MACE risk by 10%.
  • No synergistic interaction found between SPAN behaviors and MACE.
  • Modest combined SPAN behavior changes can significantly reduce cardiovascular risk.