OsGSK2-OsTCP19 Module Integrates Nitrogen and Brassinosteroid Signaling to Regulate Nitrogen Utilization and Root Growth in Rice - PubMed
3 hours ago
- #Nitrogen signaling
- #Brassinosteroids
- #Root development
- The study identifies the OsGSK2-OsTCP19 module as a key integrator of nitrogen (N) and brassinosteroid (BR) signaling pathways in rice.
- Nitrate activates BR signaling in a dose-dependent manner, with peak activity at 2.5 mM nitrate.
- BR signaling enhances nitrate signaling and lateral root elongation, dependent on the protein level of OsTCP19.
- Nitrate-induced BR signaling promotes the degradation of OsTCP19 within 2-4 hours.
- OsGSK2 interacts with and phosphorylates OsTCP19 at specific sites (Ser141 and Thr289) to stabilize it.
- OsTCP19 binds to promoters of nitrate-responsive and root development genes, negatively regulating N responses and lateral root growth.
- The findings establish a direct molecular link between nitrate and BR signaling, coordinating N utilization and root plasticity in rice.