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Interventions for Increasing Colorectal Cancer Screening Uptake: A Systematic Review and Network Meta-Analysis - PubMed

4 hours ago
  • #network meta-analysis
  • #screening interventions
  • #colorectal cancer
  • Patient navigation and mailed FIT outreach are the most effective interventions for increasing colorectal cancer screening uptake.
  • Educational multimedia and reminder-only interventions show modest effects, while choice-based and colonoscopy outreach are not significantly better than usual care.
  • In low baseline uptake settings (<30%), mailed FIT outreach is especially effective, whereas educational multimedia performs better in higher uptake populations and recent studies.
  • The analysis included 76 randomized trials, with most evidence rated moderate to low certainty.