A Scalable COF-Based Sequestrant for Synergistic Bile Acid Modulation in Fatty Liver Disease - PubMed
a day ago
- #fatty liver disease
- #COF adsorbent
- #bile acid modulation
- Development of a scalable COF-based sequestrant for bile acid modulation in fatty liver disease.
- Synergistic anion-exchange/pore-adsorption strategy enhances bile acid adsorption efficiency and selectivity.
- COF treatment outperforms clinical drug cholestyramine, avoiding nutrient loss.
- In vivo results show significant reduction in cholesterol levels and liver injury markers.
- Potential for COFs as next-generation oral adsorbents for metabolic disorders.