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Cellular and molecular basis of neuropathic pain - PubMed

7 hours ago
  • #Molecular Mechanisms
  • #Analgesics
  • #Neuropathic Pain
  • Neuropathic pain significantly reduces quality of life and shares commonalities with inflammatory pain.
  • The review covers cellular and molecular drivers, including neuronal and non-neuronal mechanisms like immune and stromal cell dysregulation.
  • Recent studies involving human cohorts are highlighted, despite challenges in accessing nervous system samples.
  • Implications for analgesic drug development in both neuropathic and non-neuropathic pain are discussed.