Metformin attenuates HSV-1-induced neuropathic pain by restoring Sirt3-mediated mitophagy - PubMed
8 hours ago
- #Metformin
- #Neuropathic Pain
- #Mitophagy
- Metformin reduces neuropathic pain caused by HSV-1 by enhancing Sirt3-driven mitophagy.
- The study highlights the role of metformin in alleviating neuroinflammation and microglia activation in HSV-1-induced pain.
- Research involved animal models with ethical approval from Naval Medical University and Shanghai Changzheng Hospital.
- No competing interests were declared by the authors, ensuring unbiased findings.
- The work references key literature on herpes zoster, postherpetic neuralgia, and related complications.