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Association of Dietary Inflammatory Index (DII) with cardiovascular and all-cause mortality in patients with Cardiovascular-Kidney-Metabolic (CKM) syndrome: a prospective cohort study - PubMed

3 hours ago
  • #Cardiovascular-Kidney-Metabolic syndrome
  • #Dietary Inflammatory Index
  • #Mortality risk
  • The study investigates the association between the Dietary Inflammatory Index (DII) and mortality in patients with Cardiovascular-Kidney-Metabolic (CKM) syndrome.
  • Higher DII scores were linked to increased risks of all-cause mortality (HR=1.24) and cardiovascular mortality (HR=1.22).
  • The research utilized data from NHANES 2003-2018, tracking 18,746 adults over a median follow-up of 8 years.
  • TyG-WC and TyG-WHtR were identified as mediators, accounting for 4.69% and 4.18% of all-cause mortality, and 13.13% and 13.96% of cardiovascular mortality, respectively.
  • The findings suggest that dietary inflammation plays a significant role in mortality risks among CKM patients, with insulin resistance indicators acting as partial mediators.