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[Conservative treatment of patients after peripheral arterial reconstruction for chronic critical limb ischemia] - PubMed

12 hours ago
  • #anticoagulants
  • #critical limb ischemia
  • #vascular surgery
  • Conservative management post-reconstructive vascular surgery is a key issue in modern medicine.
  • Study evaluates aspirin and low-dose rivaroxaban efficacy/safety in atherosclerosis patients after lower limb arterial reconstruction.
  • 182 patients (40-95 years) with chronic critical limb ischemia underwent femoropopliteal bypass surgery.
  • Patients divided into 4 groups based on operation type and postoperative therapy.
  • Follow-ups at 30 days, 3, 6, and 12 months via clinical exams and duplex ultrasound.
  • Unfavorable outcomes (e.g., limb ischemia, amputation, thrombosis) varied by group (8.3%-24.4%).
  • Major gastrointestinal bleeding occurred in 2.6% of one group, with no significant events in others.
  • Low-dose rivaroxaban with aspirin was effective and safe compared to aspirin-clopidogrel post-revascularization.