Human YTHDC2 mutations disturb RNA homeostasis of oocytes and early embryos - PubMed
4 hours ago
- #RNA homeostasis
- #YTHDC2 mutation
- #Female infertility
- Human YTHDC2 mutations disrupt RNA homeostasis in oocytes and early embryos.
- The study links YTHDC2 mutations to female infertility and defects in oocyte and early embryo competence.
- Ethical approval was obtained from the Institutional Review Board of the Center for Reproductive Medicine, Shandong University, and the Reproductive and Genetic Hospital of CITIC-XIANGYA.
- All participants provided informed consent for the study and publication of data.
- The research was supported by multiple grants from the National Natural Science Foundation of China and other funding programs.