Contrast-Associated Acute Kidney Injury After Thrombectomy for Ischemic Stroke: Prognostic Impact and CAN-REST Predictive Score - PubMed
3 days ago
- #endovascular thrombectomy
- #acute kidney injury
- #ischemic stroke
- Contrast-associated acute kidney injury (CA-AKI) occurs in approximately 1 in 20 patients undergoing endovascular thrombectomy (EVT) for acute ischemic stroke (AIS).
- CA-AKI is independently associated with higher in-hospital mortality, worse 90-day modified Rankin Scale (mRS) scores, and severe disability or death.
- A preprocedural risk model (CAN-REST score) was developed using 12 clinical variables to predict CA-AKI risk with acceptable discrimination and calibration.
- The study involved 6,638 patients across 73 centers in 16 countries, highlighting the global relevance of the findings.
- Preventive strategies for high-risk patients may improve outcomes post-EVT.