A Bayesian analysis of finerenone in heart failure with mildly reduced and preserved ejection fraction: a pre-specified analysis of FINEARTS-HF - PubMed
6 days ago
- #Finerenone
- #Heart failure
- #Bayesian analysis
- Bayesian analysis of finerenone in HFmrEF/HFpEF patients showed a reduction in cardiovascular death and heart failure events.
- Incorporating prior evidence increased the probability of a ≥10% reduction in primary event rate from 90% to 92%.
- Finerenone had an 80% probability of reducing cardiovascular death and 85% for all-cause mortality.
- The study confirmed finerenone's efficacy under both frequentist and Bayesian methods.
- Finerenone increased hyperkalaemia risk but decreased hypokalaemia probability.