Acute bronchopneumonia with Bordetella bronchiseptica bacteremia in an immunocompromised patient with bronchiectasis: A case report and review of the literature - PubMed
3 hours ago
- #Bordetella bronchiseptica
- #bronchopneumonia
- #immunocompromised
- Bordetella bronchiseptica rarely causes human disease, with bloodstream infections being exceptional.
- A case is reported of a 69-year-old immunocompromised patient with bronchiectasis who developed acute bronchopneumonia with B. bronchiseptica bacteremia.
- The patient presented with fever and productive cough despite pre-admission levofloxacin, and chest CT showed new opacities.
- Blood cultures identified B. bronchiseptica via MALDI-TOF MS and subculture, showing resistance to third-generation cephalosporins but susceptibility to piperacillin, carbapenems, and others.
- Treatment was switched to piperacillin and then oral minocycline, leading to clinical resolution after 14 days, with no animal exposure noted.
- The case highlights B. bronchiseptica as a potential pathogen in immunocompromised patients with bronchiectasis, even without animal contact, and stresses the need for susceptibility-guided therapy due to variable antibiotic resistance.