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Research progress on the compositional characteristics of the tumor immune microenvironment and immunopredictive models in esophageal squamous cell carcinoma - PubMed

7 hours ago
  • #Esophageal squamous cell carcinoma
  • #Tumor immune microenvironment
  • #Immunotherapy
  • Esophageal squamous cell carcinoma (ESCC) is a major type of esophageal cancer.
  • Immunotherapy, especially immune checkpoint inhibitors (ICIs), shows significant efficacy in advanced ESCC.
  • The tumor immune microenvironment (TIME) heterogeneity affects immunotherapy outcomes and tumor behavior.
  • Understanding TIME interactions and reshaping it with ICIs could offer new treatment opportunities.
  • The review discusses TIME characteristics and immunopredictive models to improve ESCC immunotherapy.