Combinatorial inhibition of IGF2BP3-regulated receptor tyrosine kinases offers a new therapeutic strategy for triple-negative breast cancer - PubMed
7 hours ago
- #TNBC
- #Receptor tyrosine kinase
- #IGF2BP3
- Combinatorial inhibition of IGF2BP3-regulated receptor tyrosine kinases is a new therapeutic strategy for triple-negative breast cancer (TNBC).
- The study involves TNBC patient tissue samples collected with ethical approval from the First Affiliated Hospital of Nanjing Medical University.
- Animal experiments were approved by the Animal Ethics Committee of Nanjing Medical University.
- Key keywords include Cynaroside, IGF2BP3, N6-methyladenosine, and Receptor tyrosine kinase.
- The authors declare no competing interests.
- Funding sources include the National Natural Science Foundation of China and other grants.