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Combinatorial inhibition of IGF2BP3-regulated receptor tyrosine kinases offers a new therapeutic strategy for triple-negative breast cancer - PubMed

7 hours ago
  • #TNBC
  • #Receptor tyrosine kinase
  • #IGF2BP3
  • Combinatorial inhibition of IGF2BP3-regulated receptor tyrosine kinases is a new therapeutic strategy for triple-negative breast cancer (TNBC).
  • The study involves TNBC patient tissue samples collected with ethical approval from the First Affiliated Hospital of Nanjing Medical University.
  • Animal experiments were approved by the Animal Ethics Committee of Nanjing Medical University.
  • Key keywords include Cynaroside, IGF2BP3, N6-methyladenosine, and Receptor tyrosine kinase.
  • The authors declare no competing interests.
  • Funding sources include the National Natural Science Foundation of China and other grants.