Sodium glucose co-transporter inhibition as a strategy to stabilize the microvasculature in sickle cell disease - PubMed
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- #SGLT Inhibitors
- #Sickle Cell Disease
- #Microvasculature
- Sodium glucose co-transporter (SGLT) inhibition is proposed as a strategy to stabilize the microvasculature in sickle cell disease.
- The study references beneficial effects of SGLT1/2 and SGLT2 inhibitors on vaso-occlusive events and organ damage in sickle cell disease mice.
- The research was published in Cardiovascular Research in 2026, with a DOI: 10.1093/cvr/cvag055.