Obstructive sleep apnea severity, Alzheimer's disease plasma markers, and CSF brain amyloidosis and tau pathology - PubMed
5 days ago
- #Alzheimer's disease
- #biomarkers
- #obstructive sleep apnea
- Study examines the link between obstructive sleep apnea (OSA) severity and Alzheimer's disease (AD) plasma biomarkers.
- OSA severity was found to correlate with plasma Aβ40, Aβ42, and Aβ42/Aβ40 ratios.
- Combining OSA severity with plasma Aβ42/Aβ40 improved detection of CSF amyloidosis and tau pathology.
- The research involved 120 cognitively normal older adults, with 70 having cerebrospinal fluid (CSF) data.
- Findings suggest that plasma and OSA measures could aid in non-invasive detection of AD associations.